Expression of PQLC2L in cancer - Summary - The Human Protein Atlas

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PQLC2L

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PQLC2L
Gene description	PQ loop repeat containing 2-like
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (ASC TERT1, EFO-21, LHCN-M2)
HPA (normal tissue):	Tissue enhanced (adipose tissue, thyroid gland)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA054395
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA054395

GENE INFORMATION
Gene name	PQLC2L (HGNC Symbol)
Synonyms	C3orf55
Description	PQ loop repeat containing 2-like (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q25.32
Chromosome location (bp)	157543246 - 157677749
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000174899 (version 83.38)
Entrez gene	152078
UniProt	A1A4F0 (UniProt - Evidence at transcript level)
neXtProt	NX_A1A4F0
Antibodypedia	PQLC2L antibodies

PROTEIN BROWSER

PQLC2L-001	PQLC2L-002	PQLC2L-003	PQLC2L-004	PQLC2L-006	PQLC2L-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PQLC2L-001 ENSP00000312323 ENST00000312275	A1A4F0 [Direct mapping] Putative uncharacterized protein PQLC2L Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all		118 aa 13.6 kDa	No	0
PQLC2L-002 ENSP00000420317 ENST00000459838	A1A4F0 [Direct mapping] Putative uncharacterized protein PQLC2L Show all	Predicted intracellular proteins Show all		72 aa 8 kDa	No	0
PQLC2L-003 ENSP00000413228 ENST00000449199	A1A4F0 [Direct mapping] Putative uncharacterized protein PQLC2L Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all		135 aa 15.6 kDa	No	1
PQLC2L-004 ENSP00000387918 ENST00000426338	A1A4F0 [Direct mapping] Putative uncharacterized protein PQLC2L Show all	Predicted intracellular proteins Show all		133 aa 15 kDa	No	0
PQLC2L-006 ENSP00000420049 ENST00000468043	C9JRW5 [Direct mapping] Putative uncharacterized protein PQLC2L Show all	Predicted intracellular proteins Show all		33 aa 3.7 kDa	No	0
PQLC2L-007 ENSP00000417372 ENST00000461040	C9J2K9 [Direct mapping] Putative uncharacterized protein PQLC2L Show all	Predicted intracellular proteins Show all		56 aa 6.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.