Cell atlas - C3orf33 - The Human Protein Atlas

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C3orf33

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm

Human cell
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	C3orf33
Gene description	Chromosome 3 open reading frame 33
Protein class	Predicted membrane proteins Predicted secreted proteins
Predicted localization	Membrane,Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the cytosol.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)
Additional location	In addition localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA037663
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the cytosol.

Main location

Nucleoplasm (approved)

Additional location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA037663	A-431	Nucleoplasm
	HPA037663	A-431	Cytosol
	HPA037663	U-2 OS	Nucleoplasm
	HPA037663	U-2 OS	Cytosol
	HPA037663	U-251 MG	Nucleoplasm
	HPA037663	U-251 MG	Cytosol

GENE INFORMATION
Gene name	C3orf33 (HGNC Symbol)
Synonyms	AC3-33, FLJ31139
Description	Chromosome 3 open reading frame 33 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q25.31
Chromosome location (bp)	155762617 - 155806351
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000174928 (version 83.38)
Entrez gene	285315
UniProt	Q6P1S2 (UniProt - Evidence at protein level)
neXtProt	NX_Q6P1S2
Antibodypedia	C3orf33 antibodies

PROTEIN BROWSER

C3orf33-001	C3orf33-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C3orf33-001 ENSP00000342512 ENST00000340171	Q6P1S2 [Direct mapping] Protein C3orf33 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005615 [extracellular space] GO:0016021 [integral component of membrane] GO:0051090 [regulation of sequence-specific DNA binding transcription factor activity] GO:0070373 [negative regulation of ERK1 and ERK2 cascade] Show all	294 aa 33.8 kDa	No	1
C3orf33-201 ENSP00000445446 ENST00000534941	Q6P1S2 [Direct mapping] Protein C3orf33 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0005615 [extracellular space] GO:0016021 [integral component of membrane] GO:0051090 [regulation of sequence-specific DNA binding transcription factor activity] GO:0070373 [negative regulation of ERK1 and ERK2 cascade] Show all	251 aa 29.3 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.