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Gene name

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In atlas

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CHST2
  • TISSUE

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PATHOLOGY ATLAS

GENE/PROTEIN

Dictionary

GENERAL INFORMATION

Gene name

CHST2

Gene description

Carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2

Protein class

Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Expressed in all
HPA (cell line):Cell line enhanced (ASC TERT1, HEL, HMC-1, U-266/70, WM-115)
HPA (normal tissue):Mixed

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

Pending cancer tissue analysis.

PROGNOSTIC SUMMARY

Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Expressed in all
0.020406080100120140160180200220240260280300FPKMBreast cancer (BRCA)Cervical cancer (CESC)Colorectal cancer (COAD,READ)Endometrial cancer (UCEC)Glioma (GBM)Head and neck cancer (HNSC)Liver cancer (LIHC)Lung cancer (LUAD,LUSC)Melanoma (SKCM)Ovarian cancer (OV)Pancreatic cancer (PAAD)Prostate cancer (PRAD)Renal cancer (KICH,KIRC,KIRP)Stomach cancer (STAD)Testis cancer (TGCT)Thyroid cancer (THCA)Urothelial cancer (BLCA)

PROTEIN EXPRESSION

Pending cancer tissue analysis


STAINING SUMMARY

 

GENE INFORMATION

Gene name

CHST2 (HGNC Symbol)

Synonyms

C6ST

Description

Carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 (HGNC Symbol)

Entrez gene summary

This locus encodes a sulfotransferase protein. The encoded enzyme catalyzes the sulfation of a nonreducing N-acetylglucosamine residue, and may play a role in biosynthesis of 6-sulfosialyl Lewis X antigen. [provided by RefSeq, Aug 2011]

Chromosome

3

Cytoband

q24

Chromosome location (bp)

143119331 - 143124014

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000175040 (version 83.38)

Entrez gene

9435

UniProt

Q9Y4C5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y4C5

Antibodypedia

CHST2 antibodies

PROTEIN BROWSER

CHST2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHST2-001
ENSP00000307911
ENST00000309575
Q9Y4C5 [Direct mapping]
Carbohydrate sulfotransferase 2
V9HVX9 [Target identity:100%; Query identity:100%]
Sulfotransferase
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001517 [N-acetylglucosamine 6-O-sulfotransferase activity]
GO:0005802 [trans-Golgi network]
GO:0005975 [carbohydrate metabolic process]
GO:0006044 [N-acetylglucosamine metabolic process]
GO:0006790 [sulfur compound metabolic process]
GO:0006954 [inflammatory response]
GO:0007275 [multicellular organismal development]
GO:0008146 [sulfotransferase activity]
GO:0016021 [integral component of membrane]
GO:0018146 [keratan sulfate biosynthetic process]
GO:0030203 [glycosaminoglycan metabolic process]
GO:0031228 [intrinsic component of Golgi membrane]
GO:0042339 [keratan sulfate metabolic process]
GO:0044281 [small molecule metabolic process]
Show all
530 aa
57.9 kDa
No 1

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