Tissue expression of ABO - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ABO
Gene description	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (small intestine)
GTEx:	Tissue enhanced (small intestine)
FANTOM5:	Tissue enhanced (small intestine)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (small intestine)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (small intestine)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (small intestine)

GENE INFORMATION
Gene name	ABO (HGNC Symbol)
Synonyms	A3GALNT, A3GALT1
Description	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) (HGNC Symbol)
Entrez gene summary	This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	9
Cytoband	q34.2
Chromosome location (bp)	133250401 - 133275214
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000175164 (version 83.38)
Entrez gene	28
UniProt
neXtProt
Antibodypedia	ABO antibodies

PROTEIN BROWSER

ABO-201	ABO-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABO-201 ENSP00000483018 ENST00000538324	A0A087X009 [Direct mapping] Histo-blood group ABO system transferase Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0004380 [glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity] GO:0004381 [fucosylgalactoside 3-alpha-galactosyltransferase activity] GO:0005975 [carbohydrate metabolic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016758 [transferase activity, transferring hexosyl groups] Show all	373 aa 42.9 kDa	No	1
ABO-202 ENSP00000483265 ENST00000611156	A0A087X0C2 [Direct mapping] Histo-blood group ABO system transferase Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005975 [carbohydrate metabolic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016758 [transferase activity, transferring hexosyl groups] Show all	353 aa 40.8 kDa	No	1