Cell atlas - ATG13 - The Human Protein Atlas

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ATG13

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm
	Plasma membrane

Human cell
	Cytosol
	Nucleoplasm
	Plasma Membrane

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GENERAL INFORMATION
Gene name	ATG13
Gene description	Autophagy related 13
Protein class	Cancer-related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	17
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cytosol. In addition localized to the plasma membrane & nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (approved)
Additional location	In addition localized to the Nucleoplasm (approved), Plasma membrane (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA039350
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cytosol. In addition localized to the plasma membrane & nucleoplasm.

Main location

Cytosol (approved)

Additional location

Nucleoplasm (approved), Plasma membrane (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA039350	A-431	Plasma membrane
	HPA039350	A-431	Cytosol
	HPA039350	U-2 OS	Nucleoplasm
	HPA039350	U-2 OS	Cytosol
	HPA039350	U-251 MG	Cytosol

GENE INFORMATION
Gene name	ATG13 (HGNC Symbol)
Synonyms	KIAA0652
Description	Autophagy related 13 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	p11.2
Chromosome location (bp)	46617527 - 46674818
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000175224 (version 83.38)
Entrez gene	9776
UniProt	O75143 (UniProt - Evidence at protein level)
neXtProt	NX_O75143
Antibodypedia	ATG13 antibodies

PROTEIN BROWSER

ATG13-001	ATG13-003	ATG13-004	ATG13-005	ATG13-006	ATG13-008	ATG13-017	ATG13-018	ATG13-024	ATG13-026	ATG13-027	ATG13-028	ATG13-029	ATG13-030	ATG13-031	ATG13-032	ATG13-034

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ATG13-001 ENSP00000433543 ENST00000524625	O75143 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000045 [autophagosome assembly] GO:0000407 [pre-autophagosomal structure] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0016236 [macroautophagy] GO:0019901 [protein kinase binding] GO:0098779 [mitophagy in response to mitochondrial depolarization] GO:1903955 [positive regulation of protein targeting to mitochondrion] GO:1990316 [ATG1/UKL1 kinase complex] Show all	480 aa 52.8 kDa	No	0
ATG13-003 ENSP00000433756 ENST00000529655	O75143 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000045 [autophagosome assembly] GO:0000407 [pre-autophagosomal structure] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0016236 [macroautophagy] GO:0019901 [protein kinase binding] GO:0098779 [mitophagy in response to mitochondrial depolarization] GO:1903955 [positive regulation of protein targeting to mitochondrion] GO:1990316 [ATG1/UKL1 kinase complex] Show all	480 aa 52.8 kDa	No	0
ATG13-004 ENSP00000431974 ENST00000526508	O75143 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000045 [autophagosome assembly] GO:0000407 [pre-autophagosomal structure] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0016236 [macroautophagy] GO:0019901 [protein kinase binding] GO:0098779 [mitophagy in response to mitochondrial depolarization] GO:1903955 [positive regulation of protein targeting to mitochondrion] GO:1990316 [ATG1/UKL1 kinase complex] Show all	517 aa 56.6 kDa	No	0
ATG13-005 ENSP00000434390 ENST00000530500	O75143 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000045 [autophagosome assembly] GO:0000407 [pre-autophagosomal structure] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0016236 [macroautophagy] GO:0019901 [protein kinase binding] GO:0098779 [mitophagy in response to mitochondrial depolarization] GO:1903955 [positive regulation of protein targeting to mitochondrion] GO:1990316 [ATG1/UKL1 kinase complex] Show all	401 aa 44.1 kDa	No	0
ATG13-006 ENSP00000352500 ENST00000359513	O75143 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000045 [autophagosome assembly] GO:0000407 [pre-autophagosomal structure] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0016236 [macroautophagy] GO:0019901 [protein kinase binding] GO:0098779 [mitophagy in response to mitochondrial depolarization] GO:1903955 [positive regulation of protein targeting to mitochondrion] GO:1990316 [ATG1/UKL1 kinase complex] Show all	517 aa 56.6 kDa	No	0
ATG13-008 ENSP00000432412 ENST00000528494	O75143 [Direct mapping] Autophagy-related protein 13 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000045 [autophagosome assembly] GO:0000407 [pre-autophagosomal structure] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0016236 [macroautophagy] GO:0019901 [protein kinase binding] GO:0098779 [mitophagy in response to mitochondrial depolarization] GO:1903955 [positive regulation of protein targeting to mitochondrion] GO:1990316 [ATG1/UKL1 kinase complex] Show all	550 aa 60.2 kDa	No	0
ATG13-017 ENSP00000434125 ENST00000531933	H0YDR0 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000407 [pre-autophagosomal structure] GO:0005829 [cytosol] Show all	47 aa 5.1 kDa	No	0
ATG13-018 ENSP00000436174 ENST00000525009	H0YEM7 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000407 [pre-autophagosomal structure] GO:0005829 [cytosol] Show all	193 aa 20.6 kDa	No	0
ATG13-024 ENSP00000436931 ENST00000533325	E9PPR2 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000407 [pre-autophagosomal structure] GO:0005829 [cytosol] GO:0006914 [autophagy] Show all	119 aa 13.4 kDa	No	0
ATG13-026 ENSP00000464274 ENST00000581416	J3QRL1 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000407 [pre-autophagosomal structure] GO:0005829 [cytosol] Show all	50 aa 5.7 kDa	No	0
ATG13-027 ENSP00000463808 ENST00000580238	J3KST9 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000407 [pre-autophagosomal structure] GO:0005829 [cytosol] Show all	33 aa 3.9 kDa	No	0
ATG13-028 ENSP00000464091 ENST00000582547	J3QR83 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000407 [pre-autophagosomal structure] GO:0005829 [cytosol] Show all	38 aa 4.4 kDa	No	0
ATG13-029 ENSP00000463998 ENST00000583249	J3QR16 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000407 [pre-autophagosomal structure] GO:0005829 [cytosol] Show all	27 aa 3.2 kDa	No	0
ATG13-030 ENSP00000463550 ENST00000581438	J3QLH7 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000407 [pre-autophagosomal structure] GO:0005829 [cytosol] Show all	13 aa 1.6 kDa	No	0
ATG13-031 ENSP00000462167 ENST00000577256	J3KRU6 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000407 [pre-autophagosomal structure] GO:0005829 [cytosol] Show all	56 aa 6.4 kDa	No	0
ATG13-032 ENSP00000378919 ENST00000395549	J9JIF6 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000407 [pre-autophagosomal structure] GO:0005829 [cytosol] GO:0006914 [autophagy] Show all	198 aa 22.2 kDa	No	0
ATG13-034 ENSP00000462644 ENST00000578626	J3KST9 [Direct mapping] Autophagy-related protein 13 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000407 [pre-autophagosomal structure] GO:0005829 [cytosol] Show all	33 aa 3.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.