Cell atlas - PNLIP - The Human Protein Atlas

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PNLIP

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TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	PNLIP
Gene description	Pancreatic lipase
Protein class	Enzymes FDA approved drug targets Plasma proteins Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (U-2 OS)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-2 OS) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	PNLIP (HGNC Symbol)
Synonyms	PL
Description	Pancreatic lipase (HGNC Symbol)
Entrez gene summary	This gene is a member of the lipase gene family. It encodes a carboxyl esterase that hydrolyzes insoluble, emulsified triglycerides, and is essential for the efficient digestion of dietary fats. This gene is expressed specifically in the pancreas. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	q25.3
Chromosome location (bp)	116545931 - 116567855
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000175535 (version 83.38)
Entrez gene	5406
UniProt	P16233 (UniProt - Evidence at protein level)
neXtProt	NX_P16233
Antibodypedia	PNLIP antibodies

PROTEIN BROWSER

PNLIP-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PNLIP-001 ENSP00000358223 ENST00000369221	P16233 [Direct mapping] Pancreatic triacylglycerol lipase Show all	Enzymes ENZYME proteins Hydrolases MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001523 [retinoid metabolic process] GO:0004806 [triglyceride lipase activity] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0006629 [lipid metabolic process] GO:0007603 [phototransduction, visible light] GO:0016042 [lipid catabolic process] GO:0030299 [intestinal cholesterol absorption] GO:0044241 [lipid digestion] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0052689 [carboxylic ester hydrolase activity] GO:0061365 [positive regulation of triglyceride lipase activity] Show all	465 aa 51.2 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.