Expression of C11orf68 in cancer - Summary - The Human Protein Atlas

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C11orf68

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C11orf68
Gene description	Chromosome 11 open reading frame 68
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear and/or cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA045938
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA045938

GENE INFORMATION
Gene name	C11orf68 (HGNC Symbol)
Synonyms	BLES03, P5326
Description	Chromosome 11 open reading frame 68 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q13.1
Chromosome location (bp)	65916808 - 65919117
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000175573 (version 83.38)
Entrez gene	83638
UniProt	Q9H3H3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H3H3
Antibodypedia	C11orf68 antibodies

PROTEIN BROWSER

C11orf68-001	C11orf68-002	C11orf68-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C11orf68-001 ENSP00000398350 ENST00000438576	Q9H3H3 [Direct mapping] UPF0696 protein C11orf68 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0044822 [poly(A) RNA binding] Show all	293 aa 31.5 kDa	No	0
C11orf68-002 ENSP00000409681 ENST00000449692	Q9H3H3 [Direct mapping] UPF0696 protein C11orf68 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0044822 [poly(A) RNA binding] Show all	292 aa 31.4 kDa	No	0
C11orf68-003 ENSP00000433914 ENST00000530188	Q9H3H3 [Direct mapping] UPF0696 protein C11orf68 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0044822 [poly(A) RNA binding] Show all	251 aa 27.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.