Expression of PRM1 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

PRM1

premium

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PRM1
Gene description	Protamine 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (testis cancer)
HPA (cell line):	Cell line enhanced (NB-4, U-2197)
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Distinct expression in sperms of testis.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded.
Reliability score	Supported based on 1 antibody. HPA055150
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (testis cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA055150

GENE INFORMATION
Gene name	PRM1 (HGNC Symbol)
Synonyms	CT94.1
Description	Protamine 1 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p13.13
Chromosome location (bp)	11280836 - 11281350
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000175646 (version 83.38)
Entrez gene	5619
UniProt	P04553 (UniProt - Evidence at protein level)
neXtProt	NX_P04553
Antibodypedia	PRM1 antibodies

PROTEIN BROWSER

PRM1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRM1-001 ENSP00000310515 ENST00000312511	P04553 [Direct mapping] Sperm protamine P1 Q3MN80 [Target identity:100%; Query identity:100%] Sperm protamine P1 Show all	Predicted intracellular proteins Show all	GO:0000786 [nucleosome] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006323 [DNA packaging] GO:0007275 [multicellular organismal development] GO:0007283 [spermatogenesis] GO:0030154 [cell differentiation] GO:0030261 [chromosome condensation] Show all	51 aa 6.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.