Expression of B3GNTL1 in cancer - Summary - The Human Protein Atlas

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B3GNTL1

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	B3GNTL1
Gene description	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression at variable levels in several tissue types.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA023585 , HPA024547
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA023585	HPA024547

GENE INFORMATION
Gene name	B3GNTL1 (HGNC Symbol)
Synonyms	B3GNT8
Description	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q25.3
Chromosome location (bp)	82942155 - 83051810
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000175711 (version 83.38)
Entrez gene	146712
UniProt	Q67FW5 (UniProt - Evidence at transcript level)
neXtProt	NX_Q67FW5
Antibodypedia	B3GNTL1 antibodies

PROTEIN BROWSER

B3GNTL1-001	B3GNTL1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
B3GNTL1-001 ENSP00000319979 ENST00000320865	Q67FW5 [Direct mapping] UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 A0A024R8X6 [Target identity:100%; Query identity:100%] HCG30384, isoform CRA_c Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016757 [transferase activity, transferring glycosyl groups] Show all	361 aa 40.7 kDa	No	0
B3GNTL1-002 ENSP00000461127 ENST00000576599	I3L4B6 [Direct mapping] HCG30384, isoform CRA_b; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		250 aa 28.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.