Expression of CCDC168 in cancer - Summary - The Human Protein Atlas

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CCDC168

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CCDC168
Gene description	Coiled-coil domain containing 168
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA048184 , HPA058793
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA048184	HPA058793

GENE INFORMATION
Gene name	CCDC168 (HGNC Symbol)
Synonyms	C13orf40, FLJ40176
Description	Coiled-coil domain containing 168 (HGNC Symbol)
Entrez gene summary
Chromosome	13
Cytoband	q33.1
Chromosome location (bp)	102729369 - 102759070
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000175820 (version 83.38)
Entrez gene	643677
UniProt	Q8NDH2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8NDH2
Antibodypedia	CCDC168 antibodies

PROTEIN BROWSER

CCDC168-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC168-001 ENSP00000320232 ENST00000322527	Q8NDH2 [Direct mapping] Coiled-coil domain-containing protein 168 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all		7081 aa 801.9 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.