Cell atlas - UFSP1 - The Human Protein Atlas

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UFSP1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	UFSP1
Gene description	UFM1-specific peptidase 1 (non-functional)
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Mixed
Protein evidence	Evidence at transcript level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	UFSP1 (HGNC Symbol)
Synonyms	UFSP
Description	UFM1-specific peptidase 1 (non-functional) (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that is similar to other Ufm1-specific proteases. Studies in mouse determined that Ufsp1 releases Ufm1 (ubiquitin-fold modifier 1) from its bound conjugated complexes which also makes it into an active form. Because the human UFSP1 protein is shorter on the N-terminus and lacks a conserved Cys active site, it is predicted to be non-functional.[provided by RefSeq, Nov 2009]
Chromosome	7
Cytoband	q22.1
Chromosome location (bp)	100888723 - 100889718
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000176125 (version 83.38)
Entrez gene	402682
UniProt	Q6NVU6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6NVU6
Antibodypedia	UFSP1 antibodies

PROTEIN BROWSER

UFSP1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
UFSP1-001 ENSP00000373413 ENST00000388761	Q6NVU6 [Direct mapping] Inactive Ufm1-specific protease 1 Show all	Enzymes Peptidases Cysteine-type peptidases Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0006508 [proteolysis] GO:0008150 [biological_process] GO:0016790 [thiolester hydrolase activity] GO:0070062 [extracellular exosome] GO:0071567 [UFM1 hydrolase activity] Show all	142 aa 15.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.