Fields »
ABOUT
HELP
BLOG
B3GNT4

GENERAL INFORMATION

Gene name

 B3GNT4

Gene description

 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4

Protein class

 Enzymes
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (cerebral cortex, skin)
GTEx:Not detected
FANTOM5:Group enriched (brain, caudate, cerebellum, hippocampus, kidney)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in a group of tissues, including skin, heart and skeletal muscle and CNS.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA055261
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebral cortex, skin)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (brain, caudate, cerebellum, hippocampus, kidney)

GENE INFORMATION

Gene name

 B3GNT4 (HGNC Symbol)

Synonyms

 B3GN-T4, beta3Gn-T4

Description

 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase protein family. The encoded enzyme is involved in the biosynthesis of poly-N-acetyllactosamine chains and prefers lacto-N-neotetraose as a substrate. It is a type II transmembrane protein. [provided by RefSeq, Jul 2008]

Chromosome

 12

Cytoband

 q24.31

Chromosome location (bp)

 122203543 - 122208952

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000176383 (version 83.38)

Entrez gene

 79369

UniProt

 Q9C0J1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9C0J1

Antibodypedia

 B3GNT4 antibodies

PROTEIN BROWSER
B3GNT4-001
B3GNT4-002
B3GNT4-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
B3GNT4-001
ENSP00000319636
ENST00000324189
Q9C0J1 [Direct mapping]
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4
A0A024RBT1 [Target identity:100%; Query identity:100%]
HCG2016450, isoform CRA_a
Show all
Enzymes
   ENZYME proteins
   Transferases
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   THUMBUP predicted membrane proteins
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Show all
GO:0000139 [Golgi membrane]
GO:0005975 [carbohydrate metabolic process]
GO:0006486 [protein glycosylation]
GO:0006493 [protein O-linked glycosylation]
GO:0008378 [galactosyltransferase activity]
GO:0008532 [N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016266 [O-glycan processing]
GO:0018146 [keratan sulfate biosynthetic process]
GO:0030203 [glycosaminoglycan metabolic process]
GO:0030311 [poly-N-acetyllactosamine biosynthetic process]
GO:0042339 [keratan sulfate metabolic process]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
Show all
 378 aa
42.3 kDa 		No 0
B3GNT4-002
ENSP00000438840
ENST00000546192
Q9C0J1 [Direct mapping]
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4
Show all
Enzymes
   ENZYME proteins
   Transferases
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0000139 [Golgi membrane]
GO:0005975 [carbohydrate metabolic process]
GO:0006486 [protein glycosylation]
GO:0006493 [protein O-linked glycosylation]
GO:0008378 [galactosyltransferase activity]
GO:0008532 [N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016266 [O-glycan processing]
GO:0018146 [keratan sulfate biosynthetic process]
GO:0030203 [glycosaminoglycan metabolic process]
GO:0030311 [poly-N-acetyllactosamine biosynthetic process]
GO:0042339 [keratan sulfate metabolic process]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
Show all
 353 aa
39.8 kDa 		Yes 0
B3GNT4-003
ENSP00000444534
ENST00000535274
Q9C0J1 [Direct mapping]
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4
Show all
Enzymes
   ENZYME proteins
   Transferases
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0000139 [Golgi membrane]
GO:0005975 [carbohydrate metabolic process]
GO:0006486 [protein glycosylation]
GO:0006493 [protein O-linked glycosylation]
GO:0008378 [galactosyltransferase activity]
GO:0008532 [N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016266 [O-glycan processing]
GO:0018146 [keratan sulfate biosynthetic process]
GO:0030203 [glycosaminoglycan metabolic process]
GO:0030311 [poly-N-acetyllactosamine biosynthetic process]
GO:0042339 [keratan sulfate metabolic process]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
Show all
 353 aa
39.8 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.