Expression of ZNF575 in cancer - Summary - The Human Protein Atlas

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ZNF575

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ZNF575
Gene description	Zinc finger protein 575
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (MOLT-4)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Approved based on 1 antibody. HPA051865
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

Urothelial cancer

STAINING SUMMARY

HPA051865

GENE INFORMATION
Gene name	ZNF575 (HGNC Symbol)
Synonyms	FLJ32567
Description	Zinc finger protein 575 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.31
Chromosome location (bp)	43525497 - 43536130
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000176472 (version 83.38)
Entrez gene	284346
UniProt	Q86XF7 (UniProt - Evidence at transcript level)
neXtProt	NX_Q86XF7
Antibodypedia	ZNF575 antibodies

PROTEIN BROWSER

ZNF575-001	ZNF575-002	ZNF575-005	ZNF575-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF575-001 ENSP00000413956 ENST00000458714	B3KQ07 [Direct mapping] Zinc finger protein 575; Zinc finger protein 575, isoform CRA_b; cDNA FLJ32567 fis, clone SPLEN2000072, highly similar to Zinc finger protein 575 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	344 aa 37.5 kDa	No	0
ZNF575-002 ENSP00000315870 ENST00000314228	Q86XF7 [Direct mapping] Zinc finger protein 575 A0A024R0U0 [Target identity:100%; Query identity:100%] Zinc finger protein 575, isoform CRA_a Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	245 aa 26.8 kDa	No	0
ZNF575-005 ENSP00000472578 ENST00000601282	Q86XF7 [Direct mapping] Zinc finger protein 575 A0A024R0U0 [Target identity:100%; Query identity:100%] Zinc finger protein 575, isoform CRA_a Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	245 aa 26.8 kDa	No	0
ZNF575-006 ENSP00000471083 ENST00000598080	M0R087 [Direct mapping] Zinc finger protein 575 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	101 aa 10.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.