Expression of KBTBD11 in cancer - Summary - The Human Protein Atlas

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KBTBD11

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	KBTBD11
Gene description	Kelch repeat and BTB (POZ) domain containing 11
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (renal cancer)
HPA (cell line):	Cell line enhanced (HDLM-2, SCLC-21H, THP-1, U-937)
HPA (normal tissue):	Tissue enhanced (cerebral cortex)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA051159
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (renal cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA051159

GENE INFORMATION
Gene name	KBTBD11 (HGNC Symbol)
Synonyms	KIAA0711, KLHDC7C
Description	Kelch repeat and BTB (POZ) domain containing 11 (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	p23.3
Chromosome location (bp)	1973878 - 2006936
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000176595 (version 83.38)
Entrez gene	9920
UniProt	O94819 (UniProt - Evidence at protein level)
neXtProt	NX_O94819
Antibodypedia	KBTBD11 antibodies

PROTEIN BROWSER

KBTBD11-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KBTBD11-001 ENSP00000321544 ENST00000320248	O94819 [Direct mapping] Kelch repeat and BTB domain-containing protein 11 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004842 [ubiquitin-protein transferase activity] GO:0005515 [protein binding] GO:0016567 [protein ubiquitination] GO:0031463 [Cul3-RING ubiquitin ligase complex] Show all	623 aa 65.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.