Expression of RMDN1 in cancer - Summary - The Human Protein Atlas

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RMDN1

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RMDN1
Gene description	Regulator of microtubule dynamics 1
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	11
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Approved based on 1 antibody. HPA026495
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

Urothelial cancer

STAINING SUMMARY

HPA026495

GENE INFORMATION
Gene name	RMDN1 (HGNC Symbol)
Synonyms	CGI-90, FAM82B, FLJ20665, RMD1
Description	Regulator of microtubule dynamics 1 (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	q21.3
Chromosome location (bp)	86468257 - 86514357
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000176623 (version 83.38)
Entrez gene	51115
UniProt	Q96DB5 (UniProt - Evidence at protein level)
neXtProt	NX_Q96DB5
Antibodypedia	RMDN1 antibodies

PROTEIN BROWSER

RMDN1-001	RMDN1-002	RMDN1-004	RMDN1-007	RMDN1-010	RMDN1-011	RMDN1-012	RMDN1-016	RMDN1-017	RMDN1-018	RMDN1-019

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RMDN1-001 ENSP00000385927 ENST00000406452	Q96DB5 [Direct mapping] Regulator of microtubule dynamics protein 1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000922 [spindle pole] GO:0005739 [mitochondrion] GO:0005813 [centrosome] GO:0005874 [microtubule] Show all	314 aa 35.8 kDa	No	0
RMDN1-002 ENSP00000428661 ENST00000519966	Q96DB5 [Direct mapping] Regulator of microtubule dynamics protein 1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000922 [spindle pole] GO:0005813 [centrosome] GO:0005874 [microtubule] Show all	271 aa 30.8 kDa	No	0
RMDN1-004 ENSP00000409661 ENST00000430676	Q96DB5 [Direct mapping] Regulator of microtubule dynamics protein 1 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000922 [spindle pole] GO:0005813 [centrosome] GO:0005874 [microtubule] Show all	284 aa 32.4 kDa	No	0
RMDN1-007 ENSP00000429899 ENST00000523911	E5RH53 [Direct mapping] Regulator of microtubule dynamics protein 1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005813 [centrosome] Show all	248 aa 28.6 kDa	Yes	0
RMDN1-010 ENSP00000429287 ENST00000517710	H0YBD9 [Direct mapping] Regulator of microtubule dynamics protein 1 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		159 aa 18.3 kDa	No	0
RMDN1-011 ENSP00000427818 ENST00000519247	H0YAP5 [Direct mapping] Regulator of microtubule dynamics protein 1 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		130 aa 15.1 kDa	No	0
RMDN1-012 ENSP00000428743 ENST00000521045	E5RGC8 [Direct mapping] Regulator of microtubule dynamics protein 1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		95 aa 10.8 kDa	Yes	0
RMDN1-016 ENSP00000428897 ENST00000519789	H0YB83 [Direct mapping] Regulator of microtubule dynamics protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		225 aa 25.8 kDa	No	0
RMDN1-017 ENSP00000428360 ENST00000520719	H0YB03 [Direct mapping] Regulator of microtubule dynamics protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005813 [centrosome] Show all	165 aa 19.2 kDa	No	0
RMDN1-018 ENSP00000431032 ENST00000519639	H0YC67 [Direct mapping] Regulator of microtubule dynamics protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	151 aa 17.5 kDa	No	0
RMDN1-019 ENSP00000430790 ENST00000522942	H0YC27 [Direct mapping] Regulator of microtubule dynamics protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		107 aa 12.5 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.