Fields »
ABOUT
HELP
BLOG
MYO1D

GENERAL INFORMATION

Gene name

 MYO1D

Gene description

 Myosin ID

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Cell line enhanced (CACO-2)
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.

Reliability score

 Uncertain based on 1 antibody.
HPA054744
SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (unfavourable) and renal cancer (favourable).
Urothelial cancer p<0.001
Renal cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA054744

GENE INFORMATION

Gene name

 MYO1D (HGNC Symbol)

Synonyms

 KIAA0727, myr4, PPP1R108

Description

 Myosin ID (HGNC Symbol)

Entrez gene summary

Chromosome

 17

Cytoband

 q11.2

Chromosome location (bp)

 32492522 - 32877177

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000176658 (version 83.38)

Entrez gene

 4642

UniProt

 O94832 (UniProt - Evidence at protein level)

neXtProt

 NX_O94832

Antibodypedia

 MYO1D antibodies

PROTEIN BROWSER
MYO1D-001
MYO1D-002
MYO1D-003
MYO1D-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MYO1D-001
ENSP00000324527
ENST00000318217
O94832 [Direct mapping]
Unconventional myosin-Id
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000146 [microfilament motor activity]
GO:0003774 [motor activity]
GO:0005515 [protein binding]
GO:0005516 [calmodulin binding]
GO:0005524 [ATP binding]
GO:0005768 [endosome]
GO:0005790 [smooth endoplasmic reticulum]
GO:0005903 [brush border]
GO:0008152 [metabolic process]
GO:0010923 [negative regulation of phosphatase activity]
GO:0016323 [basolateral plasma membrane]
GO:0016459 [myosin complex]
GO:0019904 [protein domain specific binding]
GO:0030424 [axon]
GO:0030673 [axolemma]
GO:0030898 [actin-dependent ATPase activity]
GO:0031410 [cytoplasmic vesicle]
GO:0043005 [neuron projection]
GO:0043025 [neuronal cell body]
GO:0043209 [myelin sheath]
GO:0044853 [plasma membrane raft]
GO:0048306 [calcium-dependent protein binding]
GO:0051015 [actin filament binding]
GO:0051641 [cellular localization]
GO:0061502 [early endosome to recycling endosome transport]
GO:0070062 [extracellular exosome]
GO:0097440 [apical dendrite]
Show all
 1006 aa
116.2 kDa 		No 0
MYO1D-002
ENSP00000464305
ENST00000579584
J3QRN6 [Direct mapping]
Unconventional myosin-Id
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 961 aa
111.3 kDa 		No 0
MYO1D-003
ENSP00000462055
ENST00000583621
J3KRL0 [Direct mapping]
Unconventional myosin-Id
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0005524 [ATP binding]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 436 aa
49.8 kDa 		No 0
MYO1D-004
ENSP00000464741
ENST00000394649
K7EIG7 [Direct mapping]
Unconventional myosin-Id
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003774 [motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0008152 [metabolic process]
GO:0016459 [myosin complex]
Show all
 918 aa
106 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.