Expression of NCKAP5 in cancer - Summary - The Human Protein Atlas

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NCKAP5

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	NCKAP5
Gene description	NCK-associated protein 5
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enriched (AF22)
HPA (normal tissue):	Tissue enhanced (lung)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA034639
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA034639

GENE INFORMATION
Gene name	NCKAP5 (HGNC Symbol)
Synonyms	ERIH1, ERIH2, NAP5
Description	NCK-associated protein 5 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q21.2
Chromosome location (bp)	132671799 - 133568463
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000176771 (version 83.38)
Entrez gene	344148
UniProt	O14513 (UniProt - Evidence at protein level)
neXtProt	NX_O14513
Antibodypedia	NCKAP5 antibodies

PROTEIN BROWSER

NCKAP5-001	NCKAP5-002	NCKAP5-004	NCKAP5-005	NCKAP5-201	NCKAP5-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NCKAP5-001 ENSP00000387128 ENST00000409261	O14513 [Direct mapping] Nck-associated protein 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005575 [cellular_component] GO:0008150 [biological_process] Show all	1909 aa 208.5 kDa	No	0
NCKAP5-002 ENSP00000386952 ENST00000409213	O14513 [Direct mapping] Nck-associated protein 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005575 [cellular_component] GO:0008150 [biological_process] Show all	590 aa 66.4 kDa	No	0
NCKAP5-004 ENSP00000399070 ENST00000427594	H7C187 [Direct mapping] Nck-associated protein 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		114 aa 13.8 kDa	No	0
NCKAP5-005 ENSP00000351882 ENST00000358991	C9JYL7 [Direct mapping] Nck-associated protein 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		69 aa 8.2 kDa	No	0
NCKAP5-201 ENSP00000380603 ENST00000317721	A0A0A0MS79 [Direct mapping] Nck-associated protein 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		1909 aa 208.5 kDa	No	0
NCKAP5-202 ENSP00000385692 ENST00000405974	A0A0A0MSE4 [Direct mapping] Nck-associated protein 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		590 aa 66.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.