Expression of GCNT4 in cancer - Summary

GENERAL INFORMATION
Gene name	GCNT4
Gene description	Glucosaminyl (N-acetyl) transferase 4, core 2
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Granular cytoplasmic expression in several tissues, including gastrointestinal tract.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA037431
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

STAINING SUMMARY

HPA037431

GENE INFORMATION
Gene name	GCNT4 (HGNC Symbol)
Synonyms	C2GNT3
Description	Glucosaminyl (N-acetyl) transferase 4, core 2 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q13.3
Chromosome location (bp)	75025346 - 75030899
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000176928 (version 83.38)
Entrez gene	51301
UniProt	Q9P109 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9P109
Antibodypedia	GCNT4 antibodies

PROTEIN BROWSER

GCNT4-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GCNT4-001 ENSP00000317027 ENST00000322348	Q9P109 [Direct mapping] Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 Show all	Enzymes ENZYME proteins Transferases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Show all	GO:0000139 [Golgi membrane] GO:0002121 [inter-male aggressive behavior] GO:0003829 [beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity] GO:0005975 [carbohydrate metabolic process] GO:0006493 [protein O-linked glycosylation] GO:0008109 [N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity] GO:0008375 [acetylglucosaminyltransferase activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016266 [O-glycan processing] GO:0042403 [thyroid hormone metabolic process] GO:0043687 [post-translational protein modification] GO:0044267 [cellular protein metabolic process] GO:0048729 [tissue morphogenesis] GO:0048872 [homeostasis of number of cells] GO:0060993 [kidney morphogenesis] Show all	453 aa 53.1 kDa	No	0