Tissue expression of TRIM60 - Summary - The Human Protein Atlas

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TRIM60

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	TRIM60
Gene description	Tripartite motif containing 60
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (placenta, testis)
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enhanced (testis)

Protein evidence

Evidence at transcript level

Protein expression

Cytoplasmic expression in cells in seminiferous ducts.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Uncertain based on 3 antibodies. HPA035809 , HPA035810 , HPA061496
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (placenta, testis)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis)

GENE INFORMATION
Gene name	TRIM60 (HGNC Symbol)
Synonyms	FLJ35882, RNF129, RNF33
Description	Tripartite motif containing 60 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. Pseudogenes of this gene are located on more than six chromosomes including chromosome 4. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2013]
Chromosome	4
Cytoband	q32.3
Chromosome location (bp)	165031953 - 165041744
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000176979 (version 83.38)
Entrez gene	166655
UniProt	Q495X7 (UniProt - Evidence at transcript level)
neXtProt	NX_Q495X7
Antibodypedia	TRIM60 antibodies

PROTEIN BROWSER

TRIM60-001	TRIM60-002	TRIM60-003	TRIM60-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TRIM60-001 ENSP00000421142 ENST00000512596	Q495X7 [Direct mapping] Tripartite motif-containing protein 60 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0008270 [zinc ion binding] Show all	471 aa 55.1 kDa	No	0
TRIM60-002 ENSP00000421784 ENST00000507119	D6RAS2 [Direct mapping] Tripartite motif-containing protein 60 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] Show all	90 aa 10.6 kDa	No	0
TRIM60-003 ENSP00000426496 ENST00000508504	Q495X7 [Direct mapping] Tripartite motif-containing protein 60 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0008270 [zinc ion binding] Show all	471 aa 55.1 kDa	No	0
TRIM60-201 ENSP00000343765 ENST00000341062	Q495X7 [Direct mapping] Tripartite motif-containing protein 60 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0008270 [zinc ion binding] Show all	471 aa 55.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.