Expression of ZDHHC22 in cancer - Summary - The Human Protein Atlas

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ZDHHC22

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	ZDHHC22
Gene description	Zinc finger, DHHC-type containing 22
Protein class	Enzymes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (glioma)
HPA (cell line):	Cell line enhanced (AF22, NTERA-2, RH-30, SCLC-21H)
HPA (normal tissue):	Tissue enriched (cerebral cortex)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (glioma)

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	ZDHHC22 (HGNC Symbol)
Synonyms	C14orf59
Description	Zinc finger, DHHC-type containing 22 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q24.3
Chromosome location (bp)	77131270 - 77142734
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000177108 (version 83.38)
Entrez gene	283576
UniProt	Q8N966 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N966
Antibodypedia	ZDHHC22 antibodies

PROTEIN BROWSER

ZDHHC22-001	ZDHHC22-002	ZDHHC22-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZDHHC22-001 ENSP00000318222 ENST00000319374	Q8N966 [Direct mapping] Palmitoyltransferase ZDHHC22 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0006612 [protein targeting to membrane] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0018230 [peptidyl-L-cysteine S-palmitoylation] GO:0018345 [protein palmitoylation] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] GO:0072659 [protein localization to plasma membrane] Show all	263 aa 29.1 kDa	No	5
ZDHHC22-002 ENSP00000450478 ENST00000555327	G3V259 [Direct mapping] Palmitoyltransferase ZDHHC22 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0016021 [integral component of membrane] Show all	41 aa 4.6 kDa	No	0
ZDHHC22-003 ENSP00000451337 ENST00000555389	G3V3N3 [Direct mapping] Palmitoyltransferase ZDHHC22 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0016021 [integral component of membrane] Show all	109 aa 11.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.