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ZBTB38
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PATHOLOGY ATLAS

GENE/PROTEIN

Dictionary

GENERAL INFORMATION

Gene name

ZBTB38

Gene description

Zinc finger and BTB domain containing 38

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

13
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Expressed in all
HPA (cell line):Cell line enhanced (RPMI-8226)
HPA (normal tissue):Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

Pending cancer tissue analysis.

PROGNOSTIC SUMMARY

Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Expressed in all
0.05.0101520253035404550FPKMBreast cancer (BRCA)Cervical cancer (CESC)Colorectal cancer (COAD,READ)Endometrial cancer (UCEC)Glioma (GBM)Head and neck cancer (HNSC)Liver cancer (LIHC)Lung cancer (LUAD,LUSC)Melanoma (SKCM)Ovarian cancer (OV)Pancreatic cancer (PAAD)Prostate cancer (PRAD)Renal cancer (KICH,KIRC,KIRP)Stomach cancer (STAD)Testis cancer (TGCT)Thyroid cancer (THCA)Urothelial cancer (BLCA)

PROTEIN EXPRESSION

Pending cancer tissue analysis


STAINING SUMMARY

 

GENE INFORMATION

Gene name

ZBTB38 (HGNC Symbol)

Synonyms

CIBZ, FLJ35036, PPP1R171, ZNF921

Description

Zinc finger and BTB domain containing 38 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a zinc finger transcriptional activator that binds methylated DNA. The encoded protein can form homodimers or heterodimers through the zinc finger domains. In mouse, inhibition of this protein has been associated with apoptosis in some cell types. [provided by RefSeq, Jun 2010]

Chromosome

3

Cytoband

q23

Chromosome location (bp)

141324213 - 141449792

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000177311 (version 83.38)

Entrez gene

253461

UniProt

Q8NAP3 (UniProt - Evidence at protein level)

neXtProt

NX_Q8NAP3

Antibodypedia

ZBTB38 antibodies

PROTEIN BROWSER

«
ZBTB38-001
ZBTB38-002
ZBTB38-005
ZBTB38-006
ZBTB38-007
ZBTB38-010
ZBTB38-012
ZBTB38-013
ZBTB38-016
ZBTB38-017
ZBTB38-018
ZBTB38-019
ZBTB38-201
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ZBTB38-001
ENSP00000426387
ENST00000514251
Q8NAP3 [Direct mapping]
Zinc finger and BTB domain-containing protein 38
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005694 [chromosome]
GO:0006275 [regulation of DNA replication]
GO:0006351 [transcription, DNA-templated]
GO:0006974 [cellular response to DNA damage stimulus]
GO:0008327 [methyl-CpG binding]
GO:0042803 [protein homodimerization activity]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046872 [metal ion binding]
GO:0072562 [blood microparticle]
Show all
1195 aa
134.3 kDa
No 0
ZBTB38-002
ENSP00000426931
ENST00000509842
D6RE69 [Direct mapping]
Zinc finger and BTB domain-containing protein 38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
150 aa
16.9 kDa
No 0
ZBTB38-005
ENSP00000424254
ENST00000509883
D6RBC4 [Direct mapping]
Zinc finger and BTB domain-containing protein 38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0005515 [protein binding]
GO:0046872 [metal ion binding]
Show all
771 aa
85.8 kDa
No 0
ZBTB38-006
ENSP00000422757
ENST00000513570
D6RAC4 [Direct mapping]
Zinc finger and BTB domain-containing protein 38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
70 aa
8 kDa
No 0
ZBTB38-007
ENSP00000406955
ENST00000441582
Q8NAP3 [Direct mapping]
Zinc finger and BTB domain-containing protein 38
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005694 [chromosome]
GO:0006275 [regulation of DNA replication]
GO:0006351 [transcription, DNA-templated]
GO:0006974 [cellular response to DNA damage stimulus]
GO:0008327 [methyl-CpG binding]
GO:0042803 [protein homodimerization activity]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046872 [metal ion binding]
GO:0072562 [blood microparticle]
Show all
1195 aa
134.3 kDa
No 0
ZBTB38-010
ENSP00000421037
ENST00000507722
D6RHD1 [Direct mapping]
Zinc finger and BTB domain-containing protein 38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
118 aa
13.3 kDa
No 0
ZBTB38-012
ENSP00000422051
ENST00000503809
D6R9J6 [Direct mapping]
Zinc finger and BTB domain-containing protein 38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
34 aa
3.9 kDa
No 0
ZBTB38-013
ENSP00000426288
ENST00000513258
D6RGK1 [Direct mapping]
Zinc finger and BTB domain-containing protein 38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
108 aa
12.3 kDa
No 0
ZBTB38-016
ENSP00000425705
ENST00000510338
D6RJE1 [Direct mapping]
Zinc finger and BTB domain-containing protein 38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
146 aa
16.4 kDa
No 0
ZBTB38-017
ENSP00000422347
ENST00000504673
D6RC86 [Direct mapping]
Zinc finger and BTB domain-containing protein 38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
94 aa
10.8 kDa
No 0
ZBTB38-018
ENSP00000422081
ENST00000510726
D6R9I1 [Direct mapping]
Zinc finger and BTB domain-containing protein 38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
210 aa
23.7 kDa
No 0
ZBTB38-019
ENSP00000422894
ENST00000509813
D6R9U6 [Direct mapping]
Zinc finger and BTB domain-containing protein 38
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
111 aa
12.5 kDa
No 0
ZBTB38-201
ENSP00000372635
ENST00000321464
Q8NAP3 [Direct mapping]
Zinc finger and BTB domain-containing protein 38
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005694 [chromosome]
GO:0006275 [regulation of DNA replication]
GO:0006351 [transcription, DNA-templated]
GO:0006974 [cellular response to DNA damage stimulus]
GO:0008327 [methyl-CpG binding]
GO:0042803 [protein homodimerization activity]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046872 [metal ion binding]
GO:0072562 [blood microparticle]
Show all
1195 aa
134.3 kDa
No 0

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