Cell atlas - NAP1L5 - The Human Protein Atlas

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NAP1L5

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm

Human cell
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	NAP1L5
Gene description	Nucleosome assembly protein 1-like 5
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the cytosol.
RNA cell category	Cell line enhanced (SH-SY5Y)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)
Additional location	In addition localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA058227
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SH-SY5Y) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the cytosol.

Main location

Nucleoplasm (approved)

Additional location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA058227	BJ	Nucleoplasm
	HPA058227	SH-SY5Y	Nucleoplasm
	HPA058227	SH-SY5Y	Cytosol
	HPA058227	U-2 OS	Nucleoplasm

GENE INFORMATION
Gene name	NAP1L5 (HGNC Symbol)
Synonyms	DRLM
Description	Nucleosome assembly protein 1-like 5 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that shares sequence similarity to nucleosome assembly factors, but may be localized to the cytoplasm rather than the nucleus. Expression of this gene is downregulated in hepatocellular carcinomas. This gene is located within a differentially methylated region (DMR) and is imprinted and paternally expressed. There is a related pseudogene on chromosome 4. [provided by RefSeq, Nov 2015]
Chromosome	4
Cytoband	q22.1
Chromosome location (bp)	88695915 - 88698235
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000177432 (version 83.38)
Entrez gene	266812
UniProt	Q96NT1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96NT1
Antibodypedia	NAP1L5 antibodies

PROTEIN BROWSER

NAP1L5-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NAP1L5-001 ENSP00000320488 ENST00000323061	Q96NT1 [Direct mapping] Nucleosome assembly protein 1-like 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006334 [nucleosome assembly] Show all	182 aa 19.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.