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GSG2

GENERAL INFORMATION

Gene name

 GSG2

Gene description

 Germ cell associated 2 (haspin)

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Mixed
HPA (normal tissue):Tissue enhanced (testis)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Nuclear and cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA027422
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Skin cancer

STAINING SUMMARY
HPA027422

GENE INFORMATION

Gene name

 GSG2 (HGNC Symbol)

Synonyms

 haspin

Description

 Germ cell associated 2 (haspin) (HGNC Symbol)

Entrez gene summary

Chromosome

 17

Cytoband

 p13.2

Chromosome location (bp)

 3723903 - 3726699

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000177602 (version 83.38)

Entrez gene

 83903

UniProt

 Q8TF76 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8TF76

Antibodypedia

 GSG2 antibodies

PROTEIN BROWSER
GSG2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GSG2-001
ENSP00000325290
ENST00000325418
Q8TF76 [Direct mapping]
Serine/threonine-protein kinase haspin
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Enzymes
   ENZYME proteins
   Transferases
   Kinases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0004672 [protein kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005694 [chromosome]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005819 [spindle]
GO:0006468 [protein phosphorylation]
GO:0007064 [mitotic sister chromatid cohesion]
GO:0035556 [intracellular signal transduction]
GO:0071459 [protein localization to chromosome, centromeric region]
GO:0072354 [histone kinase activity (H3-T3 specific)]
GO:0090231 [regulation of spindle checkpoint]
GO:2000751 [histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore]
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 798 aa
88.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.