Expression of C12orf54 in cancer - Summary - The Human Protein Atlas

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C12orf54

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C12orf54
Gene description	Chromosome 12 open reading frame 54
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Group enriched (cervical cancer, head and neck cancer, lung cancer, urothelial cancer)
HPA (cell line):	Cell line enhanced (HaCaT)
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA039919
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Group enriched (cervical cancer, head and neck cancer, lung cancer, urothelial cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA039919

GENE INFORMATION
Gene name	C12orf54 (HGNC Symbol)
Synonyms	MGC35033
Description	Chromosome 12 open reading frame 54 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q13.11
Chromosome location (bp)	48482503 - 48496512
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000177627 (version 83.38)
Entrez gene	121273
UniProt	Q6X4T0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6X4T0
Antibodypedia	C12orf54 antibodies

PROTEIN BROWSER

C12orf54-001	C12orf54-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C12orf54-001 ENSP00000447109 ENST00000548364	Q6X4T0 [Direct mapping] Uncharacterized protein C12orf54 A0A024R0Z1 [Target identity:100%; Query identity:100%] Chromosome 12 open reading frame 54, isoform CRA_a Show all	Predicted intracellular proteins Show all		127 aa 14.5 kDa	No	0
C12orf54-201 ENSP00000316898 ENST00000314014	Q6X4T0 [Direct mapping] Uncharacterized protein C12orf54 A0A024R0Z1 [Target identity:100%; Query identity:100%] Chromosome 12 open reading frame 54, isoform CRA_a Show all	Predicted intracellular proteins Show all		127 aa 14.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.