Expression of C2orf57 in cancer - Summary - The Human Protein Atlas

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C2orf57

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C2orf57
Gene description	Chromosome 2 open reading frame 57
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Selective expression in seminiferous ducts of testis.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA049917 , HPA056433
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA049917	HPA056433

GENE INFORMATION
Gene name	C2orf57 (HGNC Symbol)
Synonyms	MGC35154
Description	Chromosome 2 open reading frame 57 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q37.1
Chromosome location (bp)	231592901 - 231594283
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000177673 (version 83.38)
Entrez gene	165100
UniProt	Q53QW1 (UniProt - Evidence at protein level)
neXtProt	NX_Q53QW1
Antibodypedia	C2orf57 antibodies

PROTEIN BROWSER

C2orf57-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C2orf57-001 ENSP00000315557 ENST00000313965	Q53QW1 [Direct mapping] Uncharacterized protein C2orf57 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	395 aa 41.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.