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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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SRRM3
  • TISSUE

  • CELL

  • PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

SRRM3

Gene description

Serine/arginine repetitive matrix 3

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Mixed
HPA (cell line):Group enriched (SCLC-21H, SH-SY5Y)
HPA (normal tissue):Group enriched (adrenal gland, cerebral cortex, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

RNA-based expert annotation gave inconclusive results.

ANTIBODY IHC RELIABILITY

Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Reliability score

Uncertain based on 1 antibody.
HPA019337
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PROGNOSTIC SUMMARY

Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA019337

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Most malignant tissues displayed moderate cytoplasmic and occasional membranous immunoreactivity. Several cases of prostate, breast and ovarian cancer as well as lymphomas were strongly stained. Squamous cell carcinomas were weakly stained or negative.

GENE INFORMATION

Gene name

SRRM3 (HGNC Symbol)

Synonyms

FLJ37078

Description

Serine/arginine repetitive matrix 3 (HGNC Symbol)

Entrez gene summary

Chromosome

7

Cytoband

q11.23

Chromosome location (bp)

76201900 - 76287288

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000177679 (version 83.38)

Entrez gene

222183

UniProt

neXtProt

Antibodypedia

SRRM3 antibodies

PROTEIN BROWSER

SRRM3-001
SRRM3-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SRRM3-001
ENSP00000480851
ENST00000611745
A0A087WXA3 [Direct mapping]
Serine/arginine repetitive matrix protein 3
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
653 aa
71.6 kDa
No 0
SRRM3-002
ENSP00000483698
ENST00000464752
A0A087X0W5 [Direct mapping]
Serine/arginine repetitive matrix protein 3
Show all
Predicted intracellular proteins
Show all
109 aa
11.2 kDa
No 0

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