Expression of ASB8 in cancer - Summary - The Human Protein Atlas

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ASB8

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ASB8
Gene description	Ankyrin repeat and SOCS box containing 8
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	13
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA003299
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA003299

GENE INFORMATION
Gene name	ASB8 (HGNC Symbol)
Synonyms	FLJ21255, MGC5540
Description	Ankyrin repeat and SOCS box containing 8 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q13.11
Chromosome location (bp)	48147788 - 48181213
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000177981 (version 83.38)
Entrez gene	140461
UniProt	Q9H765 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9H765
Antibodypedia	ASB8 antibodies

PROTEIN BROWSER

ASB8-001	ASB8-002	ASB8-004	ASB8-005	ASB8-006	ASB8-007	ASB8-008	ASB8-009	ASB8-010	ASB8-013	ASB8-016	ASB8-017	ASB8-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ASB8-001 ENSP00000320893 ENST00000317697	Q9H765 [Direct mapping] Ankyrin repeat and SOCS box protein 8 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0016567 [protein ubiquitination] GO:0035556 [intracellular signal transduction] Show all	288 aa 31.6 kDa	No	0
ASB8-002 ENSP00000445622 ENST00000536549	Q9H765 [Direct mapping] Ankyrin repeat and SOCS box protein 8 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0016567 [protein ubiquitination] GO:0035556 [intracellular signal transduction] Show all	288 aa 31.6 kDa	No	0
ASB8-004 ENSP00000440773 ENST00000535055	F5GYF0 [Direct mapping] Ankyrin repeat and SOCS box protein 8 Show all	Predicted intracellular proteins Show all		85 aa 9.3 kDa	No	0
ASB8-005 ENSP00000438498 ENST00000536953	F5GYF0 [Direct mapping] Ankyrin repeat and SOCS box protein 8 Show all	Predicted intracellular proteins Show all		85 aa 9.3 kDa	No	0
ASB8-006 ENSP00000443148 ENST00000535988	F5H5S9 [Direct mapping] Ankyrin repeat and SOCS box protein 8 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	86 aa 9.6 kDa	No	0
ASB8-007 ENSP00000437530 ENST00000540782	F5H5S9 [Direct mapping] Ankyrin repeat and SOCS box protein 8 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	86 aa 9.6 kDa	No	0
ASB8-008 ENSP00000437769 ENST00000545791	F5H6A7 [Direct mapping] Ankyrin repeat and SOCS box protein 8 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	114 aa 12.5 kDa	No	0
ASB8-009 ENSP00000442737 ENST00000536071	F5H772 [Direct mapping] Ankyrin repeat and SOCS box protein 8 Show all	Predicted intracellular proteins Show all		95 aa 10.6 kDa	No	0
ASB8-010 ENSP00000442639 ENST00000540212	F5H7B4 [Direct mapping] Ankyrin repeat and SOCS box protein 8 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	112 aa 12.4 kDa	No	0
ASB8-013 ENSP00000445540 ENST00000539528	F5GYF0 [Direct mapping] Ankyrin repeat and SOCS box protein 8 Show all	Predicted intracellular proteins Show all		85 aa 9.3 kDa	No	0
ASB8-016 ENSP00000444093 ENST00000539503	F5GZZ3 [Direct mapping] Ankyrin repeat and SOCS box protein 8 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	127 aa 14 kDa	No	0
ASB8-017 ENSP00000447819 ENST00000548228	F8VS92 [Direct mapping] Ankyrin repeat and SOCS box protein 8 Show all	Predicted intracellular proteins Show all		51 aa 5.8 kDa	No	0
ASB8-201 ENSP00000486138 ENST00000629941	F5H243 [Direct mapping] Ankyrin repeat and SOCS box protein 8 Show all	Predicted intracellular proteins Show all		66 aa 7.5 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.