Expression of PRSS36 in cancer - Summary - The Human Protein Atlas

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PRSS36

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	PRSS36
Gene description	Protease, serine, 36
Protein class	Enzymes Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (HeLa)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA036079
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PROGNOSTIC SUMMARY
Prognostic marker in cervical cancer (favourable).
Cervical cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036079

GENE INFORMATION
Gene name	PRSS36 (HGNC Symbol)
Synonyms	FLJ90661
Description	Protease, serine, 36 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p11.2
Chromosome location (bp)	31138925 - 31150094
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000178226 (version 83.38)
Entrez gene	146547
UniProt	Q5K4E3 (UniProt - Evidence at protein level)
neXtProt	NX_Q5K4E3
Antibodypedia	PRSS36 antibodies

PROTEIN BROWSER

PRSS36-001	PRSS36-003	PRSS36-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRSS36-001 ENSP00000268281 ENST00000268281	Q5K4E3 [Direct mapping] Polyserase-2 Show all	Enzymes Peptidases Serine-type peptidases MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005578 [proteinaceous extracellular matrix] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	855 aa 92 kDa	Yes	0
PRSS36-003 ENSP00000454768 ENST00000569305	Q5K4E3 [Direct mapping] Polyserase-2 Show all	Enzymes Peptidases Serine-type peptidases MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005578 [proteinaceous extracellular matrix] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	850 aa 91.4 kDa	Yes	0
PRSS36-004 ENSP00000407160 ENST00000418068	Q5K4E3 [Direct mapping] Polyserase-2 Show all	Enzymes Peptidases Serine-type peptidases MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005578 [proteinaceous extracellular matrix] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	752 aa 80.9 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.