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TMEM11

GENERAL INFORMATION

Gene name

 TMEM11

Gene description

 Transmembrane protein 11

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA051795
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA051795

GENE INFORMATION

Gene name

 TMEM11 (HGNC Symbol)

Synonyms

 C17orf35, PM1, PMI

Description

 Transmembrane protein 11 (HGNC Symbol)

Entrez gene summary

Chromosome

 17

Cytoband

 p11.2

Chromosome location (bp)

 21197280 - 21214624

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000178307 (version 83.38)

Entrez gene

 8834

UniProt

 P17152 (UniProt - Evidence at protein level)

neXtProt

 NX_P17152

Antibodypedia

 TMEM11 antibodies

PROTEIN BROWSER
TMEM11-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TMEM11-001
ENSP00000319992
ENST00000317635
P17152 [Direct mapping]
Transmembrane protein 11, mitochondrial
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
GO:0005887 [integral component of plasma membrane]
GO:0007005 [mitochondrion organization]
GO:0031305 [integral component of mitochondrial inner membrane]
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 192 aa
21.5 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.