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ZNF354B

GENERAL INFORMATION

Gene name

 ZNF354B

Gene description

 Zinc finger protein 354B

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at transcript level

Protein expression
normal tissue

 General nuclear expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA029056
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and head and neck cancer (favourable).
Renal cancer p<0.001
Head and neck cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA029056

GENE INFORMATION

Gene name

 ZNF354B (HGNC Symbol)

Synonyms

 FLJ25008, KID2

Description

 Zinc finger protein 354B (HGNC Symbol)

Entrez gene summary

Chromosome

 5

Cytoband

 q35.3

Chromosome location (bp)

 178859953 - 178888122

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000178338 (version 83.38)

Entrez gene

 117608

UniProt

 Q96LW1 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q96LW1

Antibodypedia

 ZNF354B antibodies

PROTEIN BROWSER
ZNF354B-001
ZNF354B-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZNF354B-001
ENSP00000327143
ENST00000322434
Q96LW1 [Direct mapping]
Zinc finger protein 354B
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Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
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GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
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 612 aa
70.5 kDa 		No 0
ZNF354B-002
ENSP00000429827
ENST00000520377
E5RH89 [Direct mapping]
Zinc finger protein 354B
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Predicted intracellular proteins
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GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
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 134 aa
15.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.