Expression of CALML3 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

CALML3

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CALML3
Gene description	Calmodulin-like 3
Protein class	Plasma proteins Predicted intracellular proteins RAS pathway related proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Group enriched (cervical cancer, head and neck cancer, lung cancer, melanoma, urothelial cancer)
HPA (cell line):	Group enriched (A-431, hTCEpi, RPMI-8226)
HPA (normal tissue):	Tissue enhanced (esophagus, skin)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous cytoplasmic expression, most abundant in squamous epithelia.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 2 antibodies. HPA044999 , CAB010070
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Group enriched (cervical cancer, head and neck cancer, lung cancer, melanoma, urothelial cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044999	CAB010070

GENE INFORMATION
Gene name	CALML3 (HGNC Symbol)
Synonyms	CLP
Description	Calmodulin-like 3 (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	p15.1
Chromosome location (bp)	5524009 - 5526771
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000178363 (version 83.38)
Entrez gene	810
UniProt	P27482 (UniProt - Evidence at protein level)
neXtProt	NX_P27482
Antibodypedia	CALML3 antibodies

PROTEIN BROWSER

CALML3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CALML3-001 ENSP00000315299 ENST00000315238	P27482 [Direct mapping] Calmodulin-like protein 3 Show all	Predicted intracellular proteins Plasma proteins RAS pathway related proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0070062 [extracellular exosome] Show all	149 aa 16.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.