Expression of CCDC185 in cancer - Summary - The Human Protein Atlas

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CCDC185

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CCDC185
Gene description	Coiled-coil domain containing 185
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA027518
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA027518

GENE INFORMATION
Gene name	CCDC185 (HGNC Symbol)
Synonyms	C1orf65, FLJ35728
Description	Coiled-coil domain containing 185 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q41
Chromosome location (bp)	223393417 - 223395470
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000178395 (version 83.38)
Entrez gene	164127
UniProt	Q8N715 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N715
Antibodypedia	CCDC185 antibodies

PROTEIN BROWSER

CCDC185-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CCDC185-001 ENSP00000355840 ENST00000366875	Q8N715 [Direct mapping] Coiled-coil domain-containing protein 185 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	623 aa 72.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.