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Group enriched (lung cancer, pancreatic cancer, stomach cancer)
HPA (cell line):
Cell line enriched (SCLC-21H)
HPA (normal tissue):
Tissue enhanced (duodenum, small intestine)
Protein evidence
Evidence at protein level
Protein expression normal tissue
Estimation of protein expression could not be performed. View primary data.
ANTIBODY IHC RELIABILITY
Data reliability description
RNA-based expert annotation gave inconclusive results. Pending external verification. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Most cancer cells showed strong cytoplasmic positivity with a granular pattern.
GENE INFORMATION
Gene name
UCN3 (HGNC Symbol)
Synonyms
SPC, UCNIII
Description
Urocortin 3 (HGNC Symbol)
Entrez gene summary
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]