Expression of C10orf67 in cancer - Summary

GENERAL INFORMATION
Gene name	C10orf67
Gene description	Chromosome 10 open reading frame 67
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enhanced (HaCaT, SiHa)
HPA (normal tissue):	Tissue enhanced (fallopian tube, testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Cytoplasmic expression in several tissues, including nuclear expression in seminiferus ducts of testis.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA038131
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

STAINING SUMMARY

HPA038131

GENE INFORMATION
Gene name	C10orf67 (HGNC Symbol)
Synonyms	MGC46732
Description	Chromosome 10 open reading frame 67 (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	p12.2
Chromosome location (bp)	23267195 - 23344845
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000179133 (version 83.38)
Entrez gene	256815
UniProt	Q8IYJ2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IYJ2
Antibodypedia	C10orf67 antibodies

PROTEIN BROWSER

C10orf67-001	C10orf67-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C10orf67-001 ENSP00000321464 ENST00000323327	Q8IYJ2 [Direct mapping] Uncharacterized protein C10orf67 Show all	Predicted intracellular proteins Show all		185 aa 21.6 kDa	No	0
C10orf67-002 ENSP00000365683 ENST00000376500	Q5SXQ8 [Direct mapping] Uncharacterized protein C10orf67 Show all	Predicted intracellular proteins Show all		296 aa 34.9 kDa	No	0