Expression of WSCD1 in cancer - Summary

GENERAL INFORMATION
Gene name	WSCD1
Gene description	WSC domain containing 1
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	10
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Group enriched (glioma, renal cancer)
HPA (cell line):	Cell line enhanced (AF22, HUVEC TERT2, PC-3, RH-30)
HPA (normal tissue):	Tissue enhanced (cerebral cortex, spleen)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Cytoplasmic expression in several tissues, most abundant in gastrointestinal tract.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA015919
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Group enriched (glioma, renal cancer)

PROTEIN EXPRESSION

STAINING SUMMARY

HPA015919

GENE INFORMATION
Gene name	WSCD1 (HGNC Symbol)
Synonyms	KIAA0523
Description	WSC domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p13.2
Chromosome location (bp)	5772234 - 6124427
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000179314 (version 83.38)
Entrez gene	23302
UniProt	Q658N2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q658N2
Antibodypedia	WSCD1 antibodies

PROTEIN BROWSER

WSCD1-001	WSCD1-004	WSCD1-005	WSCD1-006	WSCD1-007	WSCD1-008	WSCD1-009	WSCD1-011	WSCD1-201	WSCD1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
WSCD1-001 ENSP00000460825 ENST00000574946	Q658N2 [Direct mapping] WSC domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0008146 [sulfotransferase activity] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] Show all	575 aa 65.7 kDa	Yes	0
WSCD1-004 ENSP00000458374 ENST00000574232	Q658N2 [Direct mapping] WSC domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0008146 [sulfotransferase activity] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] Show all	575 aa 65.7 kDa	Yes	0
WSCD1-005 ENSP00000460396 ENST00000573634	I3L3E6 [Direct mapping] WSC domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0008146 [sulfotransferase activity] GO:0008152 [metabolic process] Show all	459 aa 52.4 kDa	No	0
WSCD1-006 ENSP00000460041 ENST00000576083	I3L2Y9 [Direct mapping] WSC domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		181 aa 20.4 kDa	Yes	0
WSCD1-007 ENSP00000458527 ENST00000571973	I3L127 [Direct mapping] WSC domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		87 aa 9.6 kDa	Yes	0
WSCD1-008 ENSP00000461642 ENST00000576233	I3NI40 [Direct mapping] WSC domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		45 aa 5.3 kDa	Yes	0
WSCD1-009 ENSP00000460428 ENST00000576947	I3L3G4 [Direct mapping] WSC domain-containing protein 1 Show all	Predicted intracellular proteins Show all		26 aa 2.8 kDa	No	0
WSCD1-011 ENSP00000461865 ENST00000573619	I3NI40 [Direct mapping] WSC domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		45 aa 5.3 kDa	Yes	0
WSCD1-201 ENSP00000323087 ENST00000317744	Q658N2 [Direct mapping] WSC domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0008146 [sulfotransferase activity] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] Show all	575 aa 65.7 kDa	Yes	0
WSCD1-202 ENSP00000446032 ENST00000539421	Q658N2 [Direct mapping] WSC domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0008146 [sulfotransferase activity] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] Show all	575 aa 65.7 kDa	Yes	0