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DNAJB8

GENERAL INFORMATION

Gene name

 DNAJB8

Gene description

 DnaJ (Hsp40) homolog, subfamily B, member 8

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)

GENE INFORMATION

Gene name

 DNAJB8 (HGNC Symbol)

Synonyms

 CT156, MGC33884

Description

 DnaJ (Hsp40) homolog, subfamily B, member 8 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene belongs to the DNAJ/HSP40 family of proteins that regulate chaperone activity. This family member suppresses aggregation and toxicity of polyglutamine proteins, and the C-terminal tail is essential for this activity. It has been implicated as a cancer-testis antigen and as a cancer stem-like cell antigen involved in renal cell carcinoma. [provided by RefSeq, Jun 2012]

Chromosome

 3

Cytoband

 q21.3

Chromosome location (bp)

 128462439 - 128467248

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000179407 (version 83.38)

Entrez gene

 165721

UniProt

 Q8NHS0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NHS0

Antibodypedia

 DNAJB8 antibodies

PROTEIN BROWSER
DNAJB8-001
DNAJB8-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DNAJB8-001
ENSP00000316053
ENST00000319153
Q8NHS0 [Direct mapping]
DnaJ homolog subfamily B member 8
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0044183 [protein binding involved in protein folding]
GO:0051082 [unfolded protein binding]
GO:0051087 [chaperone binding]
GO:0061077 [chaperone-mediated protein folding]
GO:0090084 [negative regulation of inclusion body assembly]
Show all
 232 aa
25.7 kDa 		No 0
DNAJB8-002
ENSP00000417418
ENST00000469083
Q8NHS0 [Direct mapping]
DnaJ homolog subfamily B member 8
Show all
Predicted intracellular proteins
Show all
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0044183 [protein binding involved in protein folding]
GO:0051082 [unfolded protein binding]
GO:0051087 [chaperone binding]
GO:0061077 [chaperone-mediated protein folding]
GO:0090084 [negative regulation of inclusion body assembly]
Show all
 232 aa
25.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.