Expression of LBX2 in cancer - Summary - The Human Protein Atlas

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LBX2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	LBX2
Gene description	Ladybird homeobox 2
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (Hep G2)
HPA (normal tissue):	Tissue enhanced (duodenum, small intestine)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA044257
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044257

GENE INFORMATION
Gene name	LBX2
Synonyms
Description	Ladybird homeobox 2 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p13.1
Chromosome location (bp)	74497517 - 74503316
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000179528 (version 83.38)
Entrez gene	85474
UniProt	Q6XYB7 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6XYB7
Antibodypedia	LBX2 antibodies

PROTEIN BROWSER

LBX2-001	LBX2-002	LBX2-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LBX2-001 ENSP00000417116 ENST00000460508	Q6XYB7 [Direct mapping] Transcription factor LBX2 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] Show all	194 aa 21.4 kDa	No	0
LBX2-002 ENSP00000366789 ENST00000377566	Q6XYB7 [Direct mapping] Transcription factor LBX2 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] Show all	198 aa 21.5 kDa	No	0
LBX2-003 ENSP00000450229 ENST00000341396	G3V218 [Direct mapping] HCG1641699, isoform CRA_b; Transcription factor LBX2 Show all	Predicted intracellular proteins Show all		57 aa 6.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.