Expression of LACC1 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

LACC1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	LACC1
Gene description	Laccase (multicopper oxidoreductase) domain containing 1
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (HMC-1, TIME)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 3 antibodies. HPA040150 , HPA044211 , CAB034228
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA040150	HPA044211	CAB034228

GENE INFORMATION
Gene name	LACC1 (HGNC Symbol)
Synonyms	C13orf31, FLJ38725
Description	Laccase (multicopper oxidoreductase) domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	13
Cytoband	q14.11
Chromosome location (bp)	43879284 - 43893932
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000179630 (version 83.38)
Entrez gene	144811
UniProt	Q8IV20 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IV20
Antibodypedia	LACC1 antibodies

PROTEIN BROWSER

LACC1-001	LACC1-002	LACC1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LACC1-001 ENSP00000317619 ENST00000325686	Q8IV20 [Direct mapping] Laccase domain-containing protein 1 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		430 aa 47.8 kDa	No	0
LACC1-002 ENSP00000394179 ENST00000425906	A2A3Z5 [Direct mapping] Laccase domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		164 aa 18.7 kDa	No	0
LACC1-201 ENSP00000391747 ENST00000441843	Q8IV20 [Direct mapping] Laccase domain-containing protein 1 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		430 aa 47.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.