Tissue expression of ABCA13 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ABCA13
Gene description	ATP-binding cassette, sub-family A (ABC1), member 13
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (bone marrow)
GTEx:	Tissue enhanced (thyroid gland)
FANTOM5:	Group enriched (esophagus, lung, pituitary gland, testis, tonsil)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (bone marrow)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (thyroid gland)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (esophagus, lung, pituitary gland, testis, tonsil)

GENE INFORMATION
Gene name	ABCA13 (HGNC Symbol)
Synonyms	FLJ33876, FLJ33951
Description	ATP-binding cassette, sub-family A (ABC1), member 13 (HGNC Symbol)
Entrez gene summary	In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.[provided by RefSeq, Mar 2009]
Chromosome	7
Cytoband	p12.3
Chromosome location (bp)	48171458 - 48647496
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000179869 (version 83.38)
Entrez gene	154664
UniProt
neXtProt
Antibodypedia	ABCA13 antibodies

PROTEIN BROWSER

ABCA13-001	ABCA13-003	ABCA13-005	ABCA13-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABCA13-001 ENSP00000411096 ENST00000435803	A0A0A0MT16 [Direct mapping] ATP-binding cassette sub-family A member 13 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005524 [ATP binding] GO:0005548 [phospholipid transporter activity] GO:0005887 [integral component of plasma membrane] GO:0008152 [metabolic process] GO:0016887 [ATPase activity] GO:0017127 [cholesterol transporter activity] GO:0033344 [cholesterol efflux] GO:0033700 [phospholipid efflux] GO:0042626 [ATPase activity, coupled to transmembrane movement of substances] GO:0043231 [intracellular membrane-bounded organelle] GO:0055085 [transmembrane transport] Show all	5058 aa 576.2 kDa	No	>9
ABCA13-003 ENSP00000391042 ENST00000411975	H0Y4D2 [Direct mapping] ATP-binding cassette sub-family A member 13 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0005524 [ATP binding] GO:0005548 [phospholipid transporter activity] GO:0005887 [integral component of plasma membrane] GO:0008152 [metabolic process] GO:0016887 [ATPase activity] GO:0017127 [cholesterol transporter activity] GO:0033344 [cholesterol efflux] GO:0033700 [phospholipid efflux] GO:0042626 [ATPase activity, coupled to transmembrane movement of substances] GO:0043231 [intracellular membrane-bounded organelle] GO:0055085 [transmembrane transport] Show all	831 aa 93.4 kDa	No	7
ABCA13-005 ENSP00000389861 ENST00000435451	H7BZI9 [Direct mapping] ATP-binding cassette sub-family A member 13 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005548 [phospholipid transporter activity] GO:0005887 [integral component of plasma membrane] GO:0017127 [cholesterol transporter activity] GO:0033344 [cholesterol efflux] GO:0033700 [phospholipid efflux] GO:0042626 [ATPase activity, coupled to transmembrane movement of substances] GO:0043231 [intracellular membrane-bounded organelle] GO:0055085 [transmembrane transport] Show all	155 aa 17.2 kDa	No	4
ABCA13-008 ENSP00000442634 ENST00000544596	F5H7B7 [Direct mapping] ATP-binding cassette sub-family A member 13 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Show all	GO:0005524 [ATP binding] GO:0005548 [phospholipid transporter activity] GO:0005887 [integral component of plasma membrane] GO:0008152 [metabolic process] GO:0016887 [ATPase activity] GO:0017127 [cholesterol transporter activity] GO:0033344 [cholesterol efflux] GO:0033700 [phospholipid efflux] GO:0042626 [ATPase activity, coupled to transmembrane movement of substances] GO:0043231 [intracellular membrane-bounded organelle] GO:0055085 [transmembrane transport] Show all	2366 aa 266.9 kDa	No	>9