Expression of ZNF48 in cancer - Summary - The Human Protein Atlas

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ZNF48

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ZNF48
Gene description	Zinc finger protein 48
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA023806
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PROGNOSTIC SUMMARY
Prognostic marker in pancreatic cancer (favourable) and renal cancer (favourable).
Pancreatic cancer p<0.001 Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA023806

GENE INFORMATION
Gene name	ZNF48 (HGNC Symbol)
Synonyms	DKFZp762K013, FLJ31751, MGC43952, ZNF553
Description	Zinc finger protein 48 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p11.2
Chromosome location (bp)	30378106 - 30400108
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000180035 (version 83.38)
Entrez gene	197407
UniProt	Q96MX3 (UniProt - Evidence at protein level)
neXtProt	NX_Q96MX3
Antibodypedia	ZNF48 antibodies

PROTEIN BROWSER

ZNF48-001	ZNF48-002	ZNF48-003	ZNF48-004	ZNF48-201	ZNF48-202	ZNF48-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF48-001 ENSP00000324056 ENST00000320159	Q96MX3 [Direct mapping] Zinc finger protein 48 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	618 aa 67.8 kDa	No	0
ZNF48-002 ENSP00000432548 ENST00000524644	E9PQ92 [Direct mapping] Zinc finger protein 48 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	143 aa 16.1 kDa	No	0
ZNF48-003 ENSP00000435674 ENST00000528032	E9PJ50 [Direct mapping] Zinc finger protein 48 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	147 aa 16.5 kDa	No	0
ZNF48-004 ENSP00000417204 ENST00000495929	F8W7I7 [Direct mapping] Zinc finger protein 48 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		110 aa 12 kDa	No	0
ZNF48-201 ENSP00000483937 ENST00000612608	Q96MX3 [Direct mapping] Zinc finger protein 48 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	618 aa 67.8 kDa	No	0
ZNF48-202 ENSP00000480262 ENST00000613509	Q96MX3 [Direct mapping] Zinc finger protein 48 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	618 aa 67.8 kDa	No	0
ZNF48-203 ENSP00000479658 ENST00000622647	A0A087WVT1 [Direct mapping] Zinc finger protein 48 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	495 aa 54 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.