Expression of ANKRD18A in cancer - Summary - The Human Protein Atlas

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ANKRD18A

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ANKRD18A
Gene description	Ankyrin repeat domain 18A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (HL-60)
HPA (normal tissue):	Tissue enhanced (bone marrow, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 4 antibodies. HPA046346 , HPA046695 , HPA049923 , HPA051288
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA046346	HPA046695	HPA049923	HPA051288

GENE INFORMATION
Gene name	ANKRD18A (HGNC Symbol)
Synonyms	FLJ35740, KIAA2015
Description	Ankyrin repeat domain 18A (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	p13.1
Chromosome location (bp)	38571358 - 38620660
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000180071 (version 83.38)
Entrez gene	253650
UniProt	Q8IVF6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IVF6
Antibodypedia	ANKRD18A antibodies

PROTEIN BROWSER

ANKRD18A-001	ANKRD18A-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ANKRD18A-001 ENSP00000382610 ENST00000399703	Q8IVF6 [Direct mapping] Ankyrin repeat domain-containing protein 18A Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	992 aa 115.6 kDa	No	0
ANKRD18A-009 ENSP00000473463 ENST00000602295	R4GN29 [Direct mapping] Ankyrin repeat domain-containing protein 18A Show all	Predicted intracellular proteins Show all		401 aa 46.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.