Tissue expression of EXOC3 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	EXOC3
Gene description	Exocyst complex component 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	EXOC3 (HGNC Symbol)
Synonyms	SEC6L1, Sec6p
Description	Exocyst complex component 3 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]
Chromosome	5
Cytoband	p15.33
Chromosome location (bp)	443158 - 471937
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000180104 (version 83.38)
Entrez gene	11336
UniProt	O60645 (UniProt - Evidence at protein level)
neXtProt	NX_O60645
Antibodypedia	EXOC3 antibodies

PROTEIN BROWSER

EXOC3-001	EXOC3-004	EXOC3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EXOC3-001 ENSP00000425587 ENST00000512944	O60645 [Direct mapping] Exocyst complex component 3 A0A024QYZ6 [Target identity:100%; Query identity:100%] Exocyst complex component 3, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000145 [exocyst] GO:0000149 [SNARE binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0006887 [exocytosis] GO:0006996 [organelle organization] GO:0015031 [protein transport] GO:0030667 [secretory granule membrane] GO:0044267 [cellular protein metabolic process] GO:0051601 [exocyst localization] GO:0061024 [membrane organization] Show all	745 aa 85.6 kDa	No	0
EXOC3-004 ENSP00000422596 ENST00000508022	D6RBR9 [Direct mapping] Exocyst complex component 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000145 [exocyst] GO:0000149 [SNARE binding] GO:0006887 [exocytosis] GO:0051601 [exocyst localization] Show all	69 aa 7.8 kDa	No	0
EXOC3-201 ENSP00000323377 ENST00000315013	O60645 [Direct mapping] Exocyst complex component 3 A0A024QYZ6 [Target identity:100%; Query identity:100%] Exocyst complex component 3, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000145 [exocyst] GO:0000149 [SNARE binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0006887 [exocytosis] GO:0006996 [organelle organization] GO:0015031 [protein transport] GO:0030667 [secretory granule membrane] GO:0044267 [cellular protein metabolic process] GO:0051601 [exocyst localization] GO:0061024 [membrane organization] Show all	745 aa 85.6 kDa	No	0