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RRH

GENERAL INFORMATION

Gene name

 RRH

Gene description

 Retinal pigment epithelium-derived rhodopsin homolog

Protein class

 G-protein coupled receptors
Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Cell line enhanced (U-266/84)
HPA (normal tissue):Not detected

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 RRH (HGNC Symbol)

Synonyms

 peropsin

Description

 Retinal pigment epithelium-derived rhodopsin homolog (HGNC Symbol)

Entrez gene summary

 Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes opsin 5 and retinal G protein coupled receptor. [provided by RefSeq, Jul 2008]

Chromosome

 4

Cytoband

 q25

Chromosome location (bp)

 109827994 - 109844604

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000180245 (version 83.38)

Entrez gene

 10692

UniProt

 O14718 (UniProt - Evidence at protein level)

neXtProt

 NX_O14718

Antibodypedia

 RRH antibodies

PROTEIN BROWSER
RRH-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RRH-001
ENSP00000314992
ENST00000317735
O14718 [Direct mapping]
Visual pigment-like receptor peropsin
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G-protein coupled receptors
   GPCRs excl olfactory receptors
   Opsins
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
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GO:0004930 [G-protein coupled receptor activity]
GO:0005887 [integral component of plasma membrane]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007601 [visual perception]
GO:0007602 [phototransduction]
GO:0009881 [photoreceptor activity]
GO:0016021 [integral component of membrane]
GO:0018298 [protein-chromophore linkage]
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 337 aa
37.4 kDa 		No 7

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.