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Most malignant cells showed weak to moderate cytoplasmic immunoreactivity. Several cases of endometrial, ovarian and testicular cancers were strongly stained.
GENE INFORMATION
Gene name
FGD6 (HGNC Symbol)
Synonyms
FLJ11183, ZFYVE24
Description
FYVE, RhoGEF and PH domain containing 6 (HGNC Symbol)
F8VY01 [Direct mapping] FYVE, RhoGEF and PH domain-containing protein 6
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Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
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GO:0005089 [Rho guanyl-nucleotide exchange factor activity] GO:0035023 [regulation of Rho protein signal transduction] GO:0043547 [positive regulation of GTPase activity]
F8VQX5 [Direct mapping] FYVE, RhoGEF and PH domain-containing protein 6
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Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)
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GO:0005089 [Rho guanyl-nucleotide exchange factor activity] GO:0035023 [regulation of Rho protein signal transduction] GO:0043547 [positive regulation of GTPase activity] GO:0046872 [metal ion binding]