Expression of EIF2S3L in cancer - Summary - The Human Protein Atlas

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EIF2S3L

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	EIF2S3L
Gene description	Putative eukaryotic translation initiation factor 2 subunit 3-like protein
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (HL-60, MOLT-4, RH-30)
HPA (normal tissue):	Tissue enhanced (testis)

Protein evidence

Evidence at transcript level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	EIF2S3L
Synonyms
Description	Putative eukaryotic translation initiation factor 2 subunit 3-like protein (UniProtKB/Swiss-Prot)
Entrez gene summary
Chromosome	12
Cytoband	p13.2
Chromosome location (bp)	10505602 - 10523135
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000180574 (version 83.38)
Entrez gene
UniProt	Q2VIR3 (UniProt - Uncertain)
neXtProt	NX_Q2VIR3
Antibodypedia	EIF2S3L antibodies

PROTEIN BROWSER

EIF2S3L-001	EIF2S3L-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EIF2S3L-001 ENSP00000323063 ENST00000322446	F8W810 [Direct mapping] Uncharacterized protein Show all	Predicted intracellular proteins Show all	GO:0001731 [formation of translation preinitiation complex] GO:0003743 [translation initiation factor activity] GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0005622 [intracellular] Show all	466 aa 50.5 kDa	No	0
EIF2S3L-002 ENSP00000445077 ENST00000538173	Q2VIR3 [Target identity:100%; Query identity:100%] Putative eukaryotic translation initiation factor 2 subunit 3-like protein Show all	Predicted intracellular proteins Show all	GO:0003743 [translation initiation factor activity] GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0006413 [translational initiation] Show all	472 aa 51.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.