Cell atlas - MAB21L1 - The Human Protein Atlas

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MAB21L1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	MAB21L1
Gene description	Mab-21-like 1 (C. elegans)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Cell line enhanced (SH-SY5Y, HBF TERT88, BJ hTERT+ SV40 Large T+, BJ)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 2 antibodies. HPA049324 , HPA059864
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SH-SY5Y, HBF TERT88, BJ hTERT+ SV40 Large T+, BJ) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA049324	BJ	Nucleoplasm
HPA049324	RH-30	Nucleus
HPA049324	RH-30	Cytosol
HPA059864	BJ	Nucleoplasm
HPA059864	RH-30	No staining
HPA059864	U-2 OS	No staining

GENE INFORMATION
Gene name	MAB21L1 (HGNC Symbol)
Synonyms	CAGR1
Description	Mab-21-like 1 (C. elegans) (HGNC Symbol)
Entrez gene summary	This gene is similar to the MAB-21 cell fate-determining gene found in C. elegans. It may be involved in eye and cerebellum development, and it has been proposed that expansion of a trinucleotide repeat region in the 5' UTR may play a role in a variety of psychiatric disorders. [provided by RefSeq, Oct 2008]
Chromosome	13
Cytoband	q13.3
Chromosome location (bp)	35474182 - 35477209
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000180660 (version 83.38)
Entrez gene	4081
UniProt	Q13394 (UniProt - Evidence at protein level)
neXtProt	NX_Q13394
Antibodypedia	MAB21L1 antibodies

PROTEIN BROWSER

MAB21L1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MAB21L1-001 ENSP00000369251 ENST00000379919	Q13394 [Direct mapping] Protein mab-21-like 1 F1T0A2 [Target identity:100%; Query identity:100%] Protein mab-21-like 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0008284 [positive regulation of cell proliferation] GO:0009653 [anatomical structure morphogenesis] GO:0043010 [camera-type eye development] Show all	359 aa 41 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.