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RNA tissue category: Group enriched (endometrium, lung)
GENE INFORMATION
Gene name
AGTR2 (HGNC Symbol)
Synonyms
AT2, MRX88
Description
Angiotensin II receptor, type 2 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation. [provided by RefSeq, Jan 2010]