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MAP6D1

GENERAL INFORMATION

Gene name

 MAP6D1

Gene description

 MAP6 domain containing 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Cell line enhanced (T-47d)
HPA (normal tissue):Group enriched (cerebral cortex, skeletal muscle)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in prostate cancer (unfavourable).
Prostate cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 MAP6D1 (HGNC Symbol)

Synonyms

 FLJ12748, SL21

Description

 MAP6 domain containing 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein highly similar to the mouse MAP6 domain containing 1 protein, which is related to the STOP proteins. Based on the study of the mouse protein, the encoded protein may function as a calmodulin-regulated neuronal protein that binds and stabilizes microtubules but also associates with the Golgi membranes through N-terminal palmitoylation. [provided by RefSeq, Oct 2008]

Chromosome

 3

Cytoband

 q27.1

Chromosome location (bp)

 183815876 - 183825594

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000180834 (version 83.38)

Entrez gene

 79929

UniProt

 Q9H9H5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H9H5

Antibodypedia

 MAP6D1 antibodies

PROTEIN BROWSER
MAP6D1-001
MAP6D1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MAP6D1-001
ENSP00000314560
ENST00000318631
Q9H9H5 [Direct mapping]
MAP6 domain-containing protein 1
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000226 [microtubule cytoskeleton organization]
GO:0005516 [calmodulin binding]
GO:0005798 [Golgi-associated vesicle]
GO:0005801 [cis-Golgi network]
GO:0005874 [microtubule]
GO:0007026 [negative regulation of microtubule depolymerization]
GO:0008017 [microtubule binding]
GO:0018009 [N-terminal peptidyl-L-cysteine N-palmitoylation]
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 199 aa
21 kDa 		No 0
MAP6D1-002
ENSP00000388945
ENST00000431348
C9JPF8 [Direct mapping]
MAP6 domain containing 1, isoform CRA_b; MAP6 domain-containing protein 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0000226 [microtubule cytoskeleton organization]
GO:0005516 [calmodulin binding]
GO:0005874 [microtubule]
GO:0008017 [microtubule binding]
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 182 aa
19.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.