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OR5AK2
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PATHOLOGY ATLAS

GENE/PROTEIN

Dictionary

GENERAL INFORMATION

Gene name

OR5AK2

Gene description

Olfactory receptor, family 5, subfamily AK, member 2

Protein class

G-protein coupled receptors
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Tissue enriched (spleen)

Protein evidence

Evidence at transcript level

ANTIBODY IHC RELIABILITY

Reliability score

Pending cancer tissue analysis.

PROGNOSTIC SUMMARY

Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Pending cancer tissue analysis


STAINING SUMMARY

 

GENE INFORMATION

Gene name

OR5AK2

Synonyms

Description

Olfactory receptor, family 5, subfamily AK, member 2 (HGNC Symbol)

Entrez gene summary

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q12.1

Chromosome location (bp)

56988872 - 56989867

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000181273 (version 83.38)

Entrez gene

390181

UniProt

Q8NH90 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8NH90

Antibodypedia

OR5AK2 antibodies

PROTEIN BROWSER

OR5AK2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

OR5AK2-001
ENSP00000322784
ENST00000326855
Q8NH90 [Direct mapping]
Olfactory receptor 5AK2
Show all
G-protein coupled receptors
   Odorant/olfactory and gustatory receptors
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   GPCRHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Show all
GO:0004930 [G-protein coupled receptor activity]
GO:0004984 [olfactory receptor activity]
GO:0005549 [odorant binding]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0007186 [G-protein coupled receptor signaling pathway]
GO:0007608 [sensory perception of smell]
GO:0016021 [integral component of membrane]
GO:0050911 [detection of chemical stimulus involved in sensory perception of smell]
Show all
309 aa
34.6 kDa
No 7

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