Expression of C6orf223 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

C6orf223

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C6orf223
Gene description	Chromosome 6 open reading frame 223
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (A-431, RPTEC TERT1, THP-1)
HPA (normal tissue):	Group enriched (breast, lung)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA046117
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and liver cancer (unfavourable).
Renal cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA046117

GENE INFORMATION
Gene name	C6orf223 (HGNC Symbol)
Synonyms	MGC45491
Description	Chromosome 6 open reading frame 223 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p21.1
Chromosome location (bp)	44000580 - 44005958
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000181577 (version 83.38)
Entrez gene	221416
UniProt	Q8N319 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8N319
Antibodypedia	C6orf223 antibodies

PROTEIN BROWSER

C6orf223-002	C6orf223-003	C6orf223-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C6orf223-002 ENSP00000423262 ENST00000439969	Q8N319 [Direct mapping] Uncharacterized protein C6orf223 Show all	Predicted intracellular proteins Show all		105 aa 11.6 kDa	No	0
C6orf223-003 ENSP00000426159 ENST00000336600	Q8N319 [Direct mapping] Uncharacterized protein C6orf223 Show all	Predicted intracellular proteins Show all		242 aa 26.1 kDa	No	0
C6orf223-004 ENSP00000477091 ENST00000442114	V9GYU4 [Direct mapping] Uncharacterized protein; Uncharacterized protein C6orf223 Show all	Predicted intracellular proteins Show all		222 aa 24.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.